The parallel stories of Plato's Retreat, a Manhattan sex club for straight couples that operated from 1977 until the mid 1980s, and of Larry Levenson, the club's impresario. In present-day interviews, Larry's family talks about him, while writers, reporters, and clients talk about the club. Mixed with these interviews are still photographs and archival footage of the club, Larry's appearances on talk shows, and newspaper articles. By the late 70s, the club was in full swing, with talk of Plato's Retreats in other cities. By the end of the decade, tax problems had Larry in trouble with the IRS and changing mores gave the club a different vibe. Then AIDS became an epidemic.

Thomas Jerome Newton is a humanoid alien who comes to Earth to get water for his dying planet. He starts a high technology company to get the billions of dollars he needs to build a return spacecraft, and meets Mary-Lou, a girl who falls in love with him. He does not count on the greed and ruthlessness of business here on Earth, however.

Joe Pendleton is a football quarterback preparing to lead his team to the Superbowl when he is almost killed in an accident. An overanxious angel plucks him to heaven only to discover that he was not ready to die, and that his body has been cremated. Another body must be found without his death being discovered, and that of a recently murdered millionaire is chosen. His wife and accountant, the murderers, are confused by this development, as he buys the Los Angeles Rams in order to once again quarterback them into the Superbowl. At the same time, he falls in love with an English environmental activist who disapproves of his policies and actions.

Unable to deal with her parents, Jeannie Tyne runs away from home. Larry and Lyne Tyne search for her, and in the process meet other people whose children ran away. With their children gone, the parents are now free to rediscover/enjoy life.

Sissy Hankshaw is born with enormous thumbs that help her hitchhiking through the US from a young age...

A bombardier in World War II tries desperately to escape the insanity of the war. However, sometimes insanity is the only sane way cope with a crazy situation. Catch-22 is a parody of a "military mentality" and of a bureaucratic society in general.

A movie director-screenwriter finds a man to finance his latest project but soon discovers that the producer is actually an undercover FBI agent working on a mob sting operation.